|
|
tyramine + tetrahydrobiopterin + O2 <=> dopamine + 4a-hydroxytetrahydrobiopterin
|
1.14.16.2
tyrosine 3-monooxygenase
|
–
|
M
|
|
BRENDA:
BS417733
MetaCyc:
RXN-9978
|
|
|
|
4a-hydroxytetrahydrobiopterin <=> dihydrobiopterin + H2O
|
4.2.1.96
4a-hydroxytetrahydrobiopterin dehydratase
|
–
|
BK
|
|
BRENDA:
BR468;
BS2138
KEGG:
R04734
|
|
|
|
L-tyrosine + tetrahydrobiopterin + O2 <=> L-Dopa + 4a-hydroxytetrahydrobiopterin
|
1.14.16.2
tyrosine 3-monooxygenase
|
–
|
K
|
|
BRENDA:
BS377086
KEGG:
R07212
SABIO-RK:
7156
|
|
|
|
L-phenylalanine + tetrahydrobiopterin + O2 <=> L-tyrosine + 4a-hydroxytetrahydrobiopterin
|
1.14.16.1
phenylalanine 4-monooxygenase
|
–
|
K
|
|
BRENDA:
BS386541
KEGG:
R07211
SABIO-RK:
8496
|
|
|
|
L-tryptophan + tetrahydrobiopterin + O2 <=> 5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin
|
1.14.16.1
phenylalanine 4-monooxygenase
1.14.16.4
tryptophan 5-monooxygenase
|
–
–
|
K
|
|
BRENDA:
BS386547
KEGG:
R07213
SABIO-RK:
8593
|
|
|
|
L-phenylalanine + tetrahydrobiopterin + O2 <=> L-m-Tyr + 4a-hydroxytetrahydrobiopterin
|
1.14.16.7
phenylalanine 3-monooxygenase
|
–
|
|
|
BRENDA:
BS424873
KEGG:
R10729
|
|
|
|
L-phenylalanine + 7(R,S)-tetrahydrobiopterin + O2 <=> L-tyrosine + 4a-hydroxytetrahydrobiopterin
|
1.14.16.1
phenylalanine 4-monooxygenase
|
–
|
|
|
BRENDA:
BS451334
|
|
|
|
L-phenylalanine + 6,7-dimethyltetrahydropterin + O2 <=> L-tyrosine + 4a-hydroxytetrahydrobiopterin
|
1.14.16.1
phenylalanine 4-monooxygenase
|
–
|
|
|
BRENDA:
BS443688
|
|
|
|
L-phenylalanine + (7R)-5,6,7,8-tetrahydrobiopterin + O2 <=> L-tyrosine + 4a-hydroxytetrahydrobiopterin
|
1.14.16.1
phenylalanine 4-monooxygenase
|
–
|
|
|
BRENDA:
BS451333
|
|
|
|
L-tryptophan + tetrahydrobiopterin <=> 5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin
|
1.14.16.4
tryptophan 5-monooxygenase
|
–
|
|
|
BRENDA:
BS417195
|
|
|
|
4a-hydroxytetrahydrobiopterin <=> (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O
|
4.2.1.96
4a-hydroxytetrahydrobiopterin dehydratase
|
–
|
|
|
BRENDA:
BS399177
|
|
|
|
4a-hydroxytetrahydrobiopterin <=> pterin + H2O
|
4.2.1.96
4a-hydroxytetrahydrobiopterin dehydratase
|
–
|
|
|
BRENDA:
BS2135
|
|